STUDIES ON THE OSMOTIC FRAGILITY OF INCUBATED NORMAL AND ABNORMAL ERYTHROCYTES*
نویسندگان
چکیده
منابع مشابه
Studies on the osmotic fragility of incubated normal and abnormal erythrocytes.
The osmotic fragility of erythrocytes is known to undergo alterations when whole blood is incubated under aseptic conditions for 24 hours. The osmotic fragility of spherocytes increases considerably ( 1 ). Normal erythrocytes undergo a slight increase in fragility (2) and by contrast the osmotic fragility of leptocytes and certain other erythrocytes (3) is decreased. The sequence of events asso...
متن کاملGraphic analysis of osmotic fragility of erythrocytes.
A precise and highly reproducible method for analyzing the osmotic fragility of erythrocytes with a minute amount of blood (less than 10 mul) is described. The osmotic fragility curves are recorded with a coil planet centrifuge with accessories and a scanning photodensitometer. The recorded curves are transcribed by a DuPont Curve Resolver and their components are analyzed. Normal fragility cur...
متن کاملEffect of parathyroid hormone on osmotic fragility of human erythrocytes.
The survival of erythrocytes (RBC) is shortened in uremia, and it has been shown that calcium influx into RBC evoked crenation and increased their rigidity. The high blood levels of parathyroid hormone (PTH) may augment entry of calcium into RBC and hence affect their integrity. We examined the effect of PTH on osmotic fragility of human RBC and investigated the mechanisms through which PTH int...
متن کاملStudies on the mechanical fragility of erythrocytes. I. Normal values for infants and children.
REINHOLD, B.M., M.R.C.P., D.C.H. AND 1)AvID YI-YUNG HSIA, M.D. I ORDER to obtains a better ttnderstanding of tise factors causitsg destruction of human erythrocytes its vivo, a number of methods have beets devised to test their susceptil)ihty to destructions by various forces applied in vitro. By manipulation of temperature, pH, osmotic equilih)rium and by the addition of hemolysitis, ithas bee...
متن کاملOsmotic Fragility of Human Erythrocytes is Altered by Porphyrin Compounds
The chemical specificity of Porphyrin derivatives, Tetraphenylporphinesulfonate (TPPS), 5, 10, 15, 20-Tetrakis (4-sulfonatophenyl) porphyrinato Iron (III) Chloride (FeTPPS) and 5, 10, 15, 20-Tetrakis (4-sulfonatophenyl) porphyrinato Iron (III) nitrosyl Chloride (FeNOTPPS), on osmotic fragility of erythrocytes was examined in vitro. TPPS increased the osmotic fragility of erythrocytes more effec...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1962
ISSN: 0021-9738
DOI: 10.1172/jci104636